{"id":334,"date":"2004-08-04T07:43:55","date_gmt":"2004-08-04T11:43:55","guid":{"rendered":"http:\/\/chimeraobscura.com\/vmalt\/?p=334"},"modified":"2006-02-07T07:36:16","modified_gmt":"2006-02-07T12:36:16","slug":"phase-0","status":"publish","type":"post","link":"http:\/\/chimeraobscura.com\/vm\/phase-0","title":{"rendered":"Phase 0"},"content":{"rendered":"

Neat article in today’s NYTimes about changes in preclinical drug testing<\/a>. That subject matter may not interest you too much, but it’s part of my day job<\/a>, and I have a vested interest in seeing the pharma\/biopharma industry come up with better methods of drug discovery & development.<\/p>\n

The best part of the article is that it doesn’t politicize, mention Medicare reform or Canadian reimportation, or imply that the drug companies are venal corporations out to suck the life from the American populace. It just talks about the new developments, some of their ethical questions, and the necessity of improving the R&D return-on-investment.<\/p>\n

This is a pleasant change from the last days of Howell Raines, when the paper actually ran an opinion piece by a man who complained<\/span> that Iressa added several months to the life of his wife, who suffered from brain tumors. No, really.<\/p>\n

(Speaking of my day job<\/a>, if you follow through that link, you’ll see my magazine’s annual Top Companies report, in which my associate editor and I profiled the top 20 pharma companies and top 10 biopharmas. Y’know: if that sorta thing interests you.)<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

Neat article in today’s NYTimes about changes in preclinical drug testing. That subject matter may not interest you too much, but it’s part of my day job, and I have a vested interest in seeing the pharma\/biopharma industry come up with better methods of drug discovery & development. The best part of the article is … <\/p>\n

Continue reading “Phase 0”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[12,18],"tags":[],"class_list":["post-334","post","type-post","status-publish","format-standard","hentry","category-pharmaceuticals","category-politics-implicit"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p4C7K-5o","jetpack_likes_enabled":true,"jetpack-related-posts":[{"id":721,"url":"http:\/\/chimeraobscura.com\/vm\/vaccine-drug-whatever","url_meta":{"origin":334,"position":0},"title":"Vaccine, drug: whatever","author":"Gil","date":"November 17, 2005","format":false,"excerpt":"I don't know why I get worked up about this stuff, but there's a boneheaded editor at the NYTimes who today decided that Tamiflu is a flu vaccine. It's not. It's a drug that treats the flu. There's a world of difference. The writers of the article, Andrew Pollack and\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":1071,"url":"http:\/\/chimeraobscura.com\/vm\/drug-deal-2","url_meta":{"origin":334,"position":1},"title":"Drug Deal","author":"Gil","date":"August 9, 2006","format":false,"excerpt":"I know this story about the generic release of Plavix requires some knowledge of how the pharmaceutical industry works, but it's a really funny tale of corporate manuevering. The CEO of the generic company (Apotex) gives an interview with the Times in which he goofs on Bristol-Myers Squibb and Sanofi-Aventis\u2026","rel":"","context":"In "Big Business"","block_context":{"text":"Big Business","link":"http:\/\/chimeraobscura.com\/vm\/category\/big-business"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":1054,"url":"http:\/\/chimeraobscura.com\/vm\/and-they-said-id-never-amount-to-anything","url_meta":{"origin":334,"position":2},"title":"And they said I’d never amount to anything","author":"Gil","date":"July 27, 2006","format":false,"excerpt":"I'm interviewing a pair of companies this morning for an article in my September issue. Their combined 2005 revenues were $126 billion. One's a major drug company, the other a major healthcare distributor. Margins are a funny thing: the drug company had around $52 billion in sales, with a cost-of-goods\u2026","rel":"","context":"In "Big Business"","block_context":{"text":"Big Business","link":"http:\/\/chimeraobscura.com\/vm\/category\/big-business"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":1530,"url":"http:\/\/chimeraobscura.com\/vm\/regulatory-overkill","url_meta":{"origin":334,"position":3},"title":"Regulatory Overkill?","author":"Gil","date":"May 30, 2007","format":false,"excerpt":"[Excerpted from this month's From the Editor column at my magazine.] In last June's From the Editor page, I wrote about a scandal involving Chinese \"innovation,\" namely a rip-off that literally involved scraping a western company's name off of cell-phone chips and painting a Chinese company's name on them. I\u2026","rel":"","context":"In "Big Business"","block_context":{"text":"Big Business","link":"http:\/\/chimeraobscura.com\/vm\/category\/big-business"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":607,"url":"http:\/\/chimeraobscura.com\/vm\/patent-theft-pending","url_meta":{"origin":334,"position":4},"title":"Patent Theft Pending","author":"Gil","date":"July 7, 2005","format":false,"excerpt":"[Here's the From the Editor page for the latest issue of my magazine]In America, the July 4th holiday involves an entertaining combination of patriotic fervor and minor explosives. As a nation, we celebrate the declaration of our independence from the one country that we now call our closest ally (supposedly,\u2026","rel":"","context":"In "Pharmaceuticals"","block_context":{"text":"Pharmaceuticals","link":"http:\/\/chimeraobscura.com\/vm\/category\/big-business\/pharmaceuticals"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":295,"url":"http:\/\/chimeraobscura.com\/vm\/who-knew-2","url_meta":{"origin":334,"position":5},"title":"Who Knew?","author":"Gil","date":"July 9, 2004","format":false,"excerpt":"My From the Editor page in the July\/August issue of my day job:Who Knew?Cancer drug prices explained! (and the Gell-Mann Amnesia effect, to boot!)In June 2004, Robert Bazell, the chief science correspondent for NBC News, wrote an article called Strange Medicine on Slate.com. I've read Slate, which is owned by\u2026","rel":"","context":"In "Pharmaceuticals"","block_context":{"text":"Pharmaceuticals","link":"http:\/\/chimeraobscura.com\/vm\/category\/big-business\/pharmaceuticals"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"_links":{"self":[{"href":"http:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/posts\/334","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/comments?post=334"}],"version-history":[{"count":0,"href":"http:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/posts\/334\/revisions"}],"wp:attachment":[{"href":"http:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/media?parent=334"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/categories?post=334"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/tags?post=334"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}