{"id":1645,"date":"2007-08-29T10:12:32","date_gmt":"2007-08-29T15:12:32","guid":{"rendered":"http:\/\/chimeraobscura.com\/vm\/from-the-editor-idiots-alchemy\/"},"modified":"2008-01-29T09:39:18","modified_gmt":"2008-01-29T14:39:18","slug":"from-the-editor-idiots-alchemy","status":"publish","type":"post","link":"https:\/\/chimeraobscura.com\/vm\/from-the-editor-idiots-alchemy","title":{"rendered":"From the Editor: Idiot&#8217;s Alchemy"},"content":{"rendered":"<p>(Sorry I haven&#8217;t written much lately, dear readers. I&#8217;ve been awfully busy at work, and pretty burned-out by the time I&#8217;m home. But I&#8217;ll wrap up most of it today, and then Amy &amp; I are off on a mini-vacation. More later! Meanwhile, here&#8217;s this issue&#8217;s From the Editor column.)<\/p>\n<p><strong>Idiots&#8217; Alchemy<\/strong><\/p>\n<p><em>Making money out of nothing at all<\/em><\/p>\n<p>In keeping with last issue&#8217;s <a href=\"http:\/\/www.contractpharma.com\/articles\/2007\/07\/from-the-editor\" target=\"_blank\">Hollywood-themed editorial<\/a>, I&#8217;ve decided to write a sequel! This month, we move from blockbusters to bombs. In <a href=\"http:\/\/imdb.com\/title\/tt0102070\/\" target=\"_blank\">Hudson Hawk<\/a>, my favorite terrible movie, the archvillains plot to demolish the world banking system by flooding it with alchemically produced gold. At least, I think that&#8217;s the plot. It&#8217;s tough to follow, what with the implausible action sequences, candy-bar code-named CIA operatives (with <a href=\"http:\/\/imdb.com\/name\/nm0000325\/\" target=\"_blank\">David Caruso<\/a> as Kit Kat!), a nun-as-love-interest, and musical numbers featuring <a href=\"http:\/\/imdb.com\/name\/nm0000732\/\" target=\"_blank\">Danny Aiello<\/a> and <a href=\"http:\/\/imdb.com\/name\/nm0000246\/\" target=\"_blank\">Bruce Willis<\/a>.<\/p>\n<p>The action revolves around Darwin and Minerva Mayflower &#8212; campily played by <a href=\"http:\/\/imdb.com\/name\/nm0001290\/\" target=\"_blank\">Richard E. Grant<\/a> and <a href=\"http:\/\/imdb.com\/name\/nm0000928\/\" target=\"_blank\">Sandra Bernhard<\/a> &#8212; and their reconstruction of a lead-to-gold machine designed by Leonardo Da Vinci. Says Minerva, &#8220;After a couple of years of steady production, we&#8217;ll flood the market with so much gold that gold itself &#8212; the foundation of all finance &#8212; will lose its meaning.&#8221;<\/p>\n<p>Of course, Nixon ended the gold standard 20 years before <em>Hudson Hawk<\/em> came out, rendering the Mayflowers&#8217; plot moot. And yet it&#8217;s also eerily prescient. After all, gold <em>qua<\/em> gold doesn&#8217;t mean so much anymore, not as a &#8220;foundation of all finance.&#8221; Now it&#8217;s just another commodity in which to invest.<\/p>\n<p>What we&#8217;re left with is money itself. Funnily enough, while we&#8217;re free of gold, we haven&#8217;t gotten over alchemy. Instead of <em>la machina oro<\/em>, we have &#8220;quant funds,&#8221; those hedge funds that employ statistical models so sophisticated that they can &#8220;find winning trade strategies,&#8221; as the <a href=\"http:\/\/wsj.com\" target=\"_blank\">Wall Street Journal<\/a> puts it. From equations to money, like magic!<\/p>\n<p>Turns out one of these winning trade strategies was investing in financial instruments that were based heavily on subprime mortgages (that is, the practice of giving large loans to people who have poor credit). Some of these sophisticated investing models managed to underestimate the risk of &#8212; repeat after me &#8212; <em>giving large loans to people who have poor credit<\/em>.<\/p>\n<p>Finding themselves pummeled by margin calls and investor redemption requests (that is, investors trying to get their money out of these fabulous funds before it all disappeared), some funds required massive bailouts from their parent institutions. Outspoken financial personality Jim Cramer made the YouTube rounds by ranting about how the government needs to step in with an interest reduction, ostensibly to save the homes of subprime mortgage holders, but also to save the jobs of hedge fund managers.<\/p>\n<p>Evaluating risk &#8212; the true foundation of finance &#8212; lost its meaning. For a while.<\/p>\n<p>So how does this tie into pharma? Well, first there&#8217;s the direct impact of this credit shakeup on private equity firms. Many of these groups employ leveraging techniques to (partially) fund acquisitions of public companies. We&#8217;ve seen several contract manufacturers acquired by PE firms this year, but with money less easy to borrow, will further acquisitions be back-burnered?<\/p>\n<p>But the other pharma tie-in is potentially more damaging, and that&#8217;s the bizarre talk about a new round of mega-mergers in the drug industry. First we heard rumors of Novartis&#8217; interest in buying Bayer, and then an analyst floated the idea that Pfizer should acquire Wyeth.<\/p>\n<p>Regarding the former, you can learn more with Derek Lowe&#8217;s <a href=\"http:\/\/pipeline.corante.com\/archives\/2007\/08\/21\/ah_rumors.php\" target=\"_blank\"><em>In the Pipeline<\/em><\/a> excerpt on page 40. As far as the latter? Well, I think the argument for a Pfizer\/Wyeth hookup is far more flawed than that which guided Pfizer&#8217;s Warner-Lambert and Pharmacia buys earlier this decade. In those instances, Pfizer could point to its co-marketing agreements for major drugs and show how 100% control of those products would lead to greater sales. You may recall that I disagreed with those moves, not that I take any joy in how that turned out.<\/p>\n<p>Now? Pfizer&#8217;s key motivation (says our analyst) is the acquisition of Wyeth&#8217;s biologics program, which she compares to AstraZeneca&#8217;s MedImmune acquisition. Which cost more than a dozen times MedImmune&#8217;s earnings. In cash.<\/p>\n<p>But I&#8217;m starting to think that the point of these rumors  &#8212; and there&#8217;ll be more this year &#8212; isn&#8217;t to push for those particular mergers. Rather, it&#8217;s to incite any sort of big merger activity, because the banks that took a bath this summer need to boost their financing and underwriting businesses this fall.<\/p>\n<p>Let&#8217;s hope the new CFOs are smart enough to keep the industry&#8217;s recent merger history in mind. Otherwise, we could be looking more upheaval. Or, as Darwin Mayflower put it in <em>Hudson Hawk<\/em>, &#8220;History, tradition, culture: these are not concepts! These are trophies I keep in my den as paperweights! The chaos we cause the world with this machine will be our final masterpiece! Go, team, go!&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>(Sorry I haven&#8217;t written much lately, dear readers. I&#8217;ve been awfully busy at work, and pretty burned-out by the time I&#8217;m home. But I&#8217;ll wrap up most of it today, and then Amy &amp; I are off on a mini-vacation. More later! Meanwhile, here&#8217;s this issue&#8217;s From the Editor column.) Idiots&#8217; Alchemy Making money out &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/chimeraobscura.com\/vm\/from-the-editor-idiots-alchemy\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;From the Editor: Idiot&#8217;s Alchemy&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jetpack_post_was_ever_published":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[27,12],"tags":[],"class_list":["post-1645","post","type-post","status-publish","format-standard","hentry","category-big-business","category-pharmaceuticals"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p4C7K-qx","jetpack_likes_enabled":true,"jetpack-related-posts":[{"id":1251,"url":"https:\/\/chimeraobscura.com\/vm\/sweet-relief","url_meta":{"origin":1645,"position":0},"title":"Sweet Relief","author":"Gil","date":"December 19, 2006","format":false,"excerpt":"It's over: the year-end issue clocked in at 406 pages, and it's all out the door (except for a couple of house ads that our art dept. is putting together)! I officially apologize to everyone whose e-mails I've failed to reply to, and I also apologize in advance for the\u2026","rel":"","context":"Similar post","block_context":{"text":"Similar post","link":""},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":8870,"url":"https:\/\/chimeraobscura.com\/vm\/episode-123-the-hidden-wish-of-words","url_meta":{"origin":1645,"position":1},"title":"Episode 123 &#8211; The Hidden Wish of Words","author":"Gil","date":"June 29, 2015","format":false,"excerpt":"Virtual Memories Show #123: Langdon Hammer - The Hidden Wish of Words \"What I really cared about most, what drew me, was the relationship between lives and work, between how we live and what we do, and what we do with it. And that's one of James Merrill's major subjects.\"\u2026","rel":"","context":"In &quot;literature&quot;","block_context":{"text":"literature","link":"https:\/\/chimeraobscura.com\/vm\/category\/literature"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/chimeraobscura.com\/vm\/wp-content\/uploads\/18591749704_288fd2b3de_o.jpg?fit=1200%2C779&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/chimeraobscura.com\/vm\/wp-content\/uploads\/18591749704_288fd2b3de_o.jpg?fit=1200%2C779&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/chimeraobscura.com\/vm\/wp-content\/uploads\/18591749704_288fd2b3de_o.jpg?fit=1200%2C779&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/chimeraobscura.com\/vm\/wp-content\/uploads\/18591749704_288fd2b3de_o.jpg?fit=1200%2C779&ssl=1&resize=700%2C400 2x, https:\/\/i0.wp.com\/chimeraobscura.com\/vm\/wp-content\/uploads\/18591749704_288fd2b3de_o.jpg?fit=1200%2C779&ssl=1&resize=1050%2C600 3x"},"classes":[]},{"id":5149,"url":"https:\/\/chimeraobscura.com\/vm\/well-my-arms-pretty-thor","url_meta":{"origin":1645,"position":2},"title":"Well, my arm&#8217;s pretty Thor","author":"Gil","date":"March 25, 2010","format":false,"excerpt":"I'm having a not-so-good reaction to a tetanus shot I had on Tuesday at my annual physical. My arm & shoulder hurt like a mo'fo', and I've got chills & exhaustion that comes and goes. I'm particularly wiped out in the evening, so I spent last night and this early\u2026","rel":"","context":"In &quot;Comic books &amp; strips&quot;","block_context":{"text":"Comic books &amp; strips","link":"https:\/\/chimeraobscura.com\/vm\/category\/literature\/comics"},"img":{"alt_text":"","src":"http:\/\/www.assoc-amazon.com\/e\/ir?t=virtualmemories-20&l=as2&o=1&a=0785118667","width":350,"height":200},"classes":[]},{"id":14594,"url":"https:\/\/chimeraobscura.com\/vm\/episode-444-jonathan-baylis","url_meta":{"origin":1645,"position":3},"title":"Episode 444 &#8211; Jonathan Baylis","author":"Gil","date":"July 20, 2021","format":"audio","excerpt":"Virtual Memories Show 444: Jonathan Baylis Writer Jonathan Baylis joins the show (in person!) to celebrate the latest issue of his autobio comics series, So Buttons (Tinto Press\/Alchemy Comix). We talk about how he found a home in the Pekar mode, writing scripts for cartoonists to draw, and how he\u2026","rel":"","context":"In &quot;Comic books &amp; strips&quot;","block_context":{"text":"Comic books &amp; strips","link":"https:\/\/chimeraobscura.com\/vm\/category\/literature\/comics"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/chimeraobscura.com\/vm\/wp-content\/uploads\/bayliscomp.jpg?fit=1200%2C480&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/chimeraobscura.com\/vm\/wp-content\/uploads\/bayliscomp.jpg?fit=1200%2C480&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/chimeraobscura.com\/vm\/wp-content\/uploads\/bayliscomp.jpg?fit=1200%2C480&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/chimeraobscura.com\/vm\/wp-content\/uploads\/bayliscomp.jpg?fit=1200%2C480&ssl=1&resize=700%2C400 2x, https:\/\/i0.wp.com\/chimeraobscura.com\/vm\/wp-content\/uploads\/bayliscomp.jpg?fit=1200%2C480&ssl=1&resize=1050%2C600 3x"},"classes":[]},{"id":10813,"url":"https:\/\/chimeraobscura.com\/vm\/episode-244-nicholas-delbanco","url_meta":{"origin":1645,"position":4},"title":"Episode 244 &#8211; Nicholas Delbanco","author":"Gil","date":"November 12, 2017","format":"audio","excerpt":"Virtual Memories Show 244: Nicholas Delbanco \"It's a rare day when I'm not at my desk by 6.\" He's been blackening the blank page for more than 50 years, and now Nicholas Delbanco joins The Virtual Memories Show to talk about writing, teaching, and sleepwalking through life! We get into\u2026","rel":"","context":"In &quot;Art&quot;","block_context":{"text":"Art","link":"https:\/\/chimeraobscura.com\/vm\/category\/art"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/chimeraobscura.com\/vm\/wp-content\/uploads\/IMG_0340.jpg?fit=1200%2C1200&ssl=1&resize=350%2C200","width":350,"height":200,"srcset":"https:\/\/i0.wp.com\/chimeraobscura.com\/vm\/wp-content\/uploads\/IMG_0340.jpg?fit=1200%2C1200&ssl=1&resize=350%2C200 1x, https:\/\/i0.wp.com\/chimeraobscura.com\/vm\/wp-content\/uploads\/IMG_0340.jpg?fit=1200%2C1200&ssl=1&resize=525%2C300 1.5x, https:\/\/i0.wp.com\/chimeraobscura.com\/vm\/wp-content\/uploads\/IMG_0340.jpg?fit=1200%2C1200&ssl=1&resize=700%2C400 2x, https:\/\/i0.wp.com\/chimeraobscura.com\/vm\/wp-content\/uploads\/IMG_0340.jpg?fit=1200%2C1200&ssl=1&resize=1050%2C600 3x"},"classes":[]},{"id":7734,"url":"https:\/\/chimeraobscura.com\/vm\/in-a-perfect-world","url_meta":{"origin":1645,"position":5},"title":"In a Perfect World","author":"Gil","date":"March 2, 2014","format":false,"excerpt":"Last Friday was my final day at my job. I quit it to launch a new business (sorta; it's complicated). The last time I was unemployed was 1995. I was 24, finished grad school in May, moved back to NJ, and started looking for a gig. I pored over the\u2026","rel":"","context":"In &quot;literature&quot;","block_context":{"text":"literature","link":"https:\/\/chimeraobscura.com\/vm\/category\/literature"},"img":{"alt_text":"","src":"http:\/\/ir-na.amazon-adsystem.com\/e\/ir?t=voyantpublishing&l=as2&o=1&a=1564786919","width":350,"height":200},"classes":[]}],"_links":{"self":[{"href":"https:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/posts\/1645","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/comments?post=1645"}],"version-history":[{"count":0,"href":"https:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/posts\/1645\/revisions"}],"wp:attachment":[{"href":"https:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/media?parent=1645"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/categories?post=1645"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/chimeraobscura.com\/vm\/wp-json\/wp\/v2\/tags?post=1645"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}